Currently, they inserted the CRISPR-Cas9 system and the

we have different techniques to use in gene editing. One of these techniques
employs the CRISPR-Cas9 technology. The CRISPR-Cas9 system uses a guide
sequence to cut a specific DNA sequence. This method had the potential for gene
editing as is could be used to target and cut specific disease-causing
sequences, replacing those sequences with healthy ones. If scientists change
the guide sequence, CRISPR-Cas9 could be used to target and cut a specific
sequence and replace it with a healthy one.

            Scientists have been able to use the
CRISPR-Cas9 system to successfully remove a dangerous mutation in human
embryos. At first, they tried inserting the CRISPR-Cas9 system into fertilized
eggs. This resulted in thirty-six of the fifty-four tested embryos without the
mutation and another thirteen of the embryos without the mutation but not in
every cell. Following this the scientists decided to try acting at an earlier
stage in an attempt to increase the number of mutation-free embryos. In the
second method, they inserted the CRISPR-Cas9 system and the sperm
simultaneously into the egg. This resulted in forty-two of the fifty-four
embryos containing two copies of the gene that were mutation free. The embryos
also contained no unwanted mutations. This is a great advancement in technique
that would allow scientists to potentially remove more DNA sequences that cause
fatal diseases.

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            With the successful editing of a
dangerous mutation in human embryos responsible for heart disease in human
embryos, this introduce the potential for gene editing of other genes and
mutations that would cause other diseases or fatal conditions. However, once
the technology becomes advanced enough, this could also cause people to try to
produce what is called a designer baby. People may try to enhance certain
qualities of the future child, such as intelligence, artistic ability, or
athleticism. In addition to these traits, people could also be preferential
about the child’s eye color, skin tone, hair, or even height. Modifying these
traits could lead to a loss of diversity in the human genome. People with
modified traits would pass them on to their offspring, who may or may not
utilize gene editing for their own children as well. Eventually, the traits
that were chosen would become more common than the supposed undesirable traits.
Those traits would eventually be lost, decreasing the diversity among people. All
this may also lead to a type of discrimination between people with the
preferred traits and those without them. People could become less tolerant of
others who do not have the same qualities as them, similar to how people have
been discriminated against on the basis of race, ethnicity, and even gender. The
technology could also result in ethical dilemmas regarding whether or not particular
genes should be chosen for a child before it is born. It would be hard to draw
a line between using the method for correcting certain diseases and using it to
alter specific genes with the goal of a child expressing a specific trait.

            Altogether, the CRISPR-Cas9 system
is a great technology used for gene editing. The system has been used in the
past to study genes and how bacteria use it for adaptive immunity against
viruses. Since the system was used to successfully edit and remove a dangerous
mutation from human embryos, potential for the system in the area of gene
editing has increased dramatically. Once the technology and procedures have
become more developed and advanced, it holds the potential to assist in the
editing and removal of genes and sequences that are known to cause disease and
fatal conditions in humans. However, this could also lead to the pursuit of a
perfect conception of designer babies. The advancement of CRISPR-Cas9 will
raise many questions, some of which will be either biomedical or ethical or
even both.


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